Isotopically Labeled Compounds
Medchemexpress LLC Cefoperazone-d5 | 2410425-70-4 | 98.6% | 1 MG
Cefoperazone-d5 is a deuterium-labeled form of Cefoperazone, a semisynthetic cephalosporin known for its broad-spectrum antibacterial activity. This compound is intended for research use only, primarily as a tracer or an internal standard in quantitative analytical methods.
- Deuterium labeled cefoperazone
- Semisynthetic cephalosporin with broad-spectrum antibacterial activity
- Functions as a tracer in research
- Used as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Incorporates stable heavy isotopes for drug development quantitation
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- Targets β-lactam
Medchemexpress LLC Adenosine-d13 | 58-61-7 | 96.6% | 1 MG
Adenosine-d13 is a deuterium-labeled version of Adenosine, a widely present endogenous autacoid. It functions by activating four G protein-coupled receptors (A1, A2A, A2B, and A3), influencing various cellular physiological processes including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. This compound is intended for research use only.
- Can be used as a tracer or internal standard for quantitative analysis.
- Suitable for techniques like NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes, such as deuterium, into drug molecules may impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC Guanosine 3',5'-cyclic monophosphate (13C,15N2) | MFCD00070129 | 348.18 g·mol⁻1 | C913CH12N315N2O7P | 500 UG
Cyclic GMP-13C,15N2 is a stable-isotope labeled guanosine 3',5'-cyclic monophosphate (cGMP) with 13C and 15N substitutions, supplied as a 500 μg vial. It is intended for use as an internal standard or tracer in quantitative mass spectrometry and metabolic studies of cGMP signaling. Molecular weight 348.18 g·mol⁻1; refer to the certificate of analysis for purity and storage instructions.
- Stable-isotope labeled (13C, 15N) for accurate quantitation.
- Suitable as an internal standard for LC-MS/MS and other analytical methods.
- Supplied as a 500 μg vial for trace-level assays.
- Certificate of analysis available for lot-specific purity and storage conditions.
- Supports studies of nitric oxide and natriuretic peptide signaling pathways.
Medchemexpress LLC Phenindione-d5 | 70711-53-4 | 99.5% | 1 MG
Phenindione-d5 is deuterium labeled Phenindione, an anticoagulant that functions as a Vitamin K antagonist. It is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Lactate-d4 sodium | 344299-52-1 | 99.0% | 5 MG
Lactic acid-d4 sodium (60% in water) is a deuterium-labeled form of lactic acid sodium. The unlabeled compound is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator that induces lysine residue lactylation. It serves as a glycolysis end-product, bridging glycolysis and oxidative phosphorylation. It is also recognized as an oncometabolite with an immune-protective role in anti-tumor immunity and possesses antimicrobial activity, making it suitable as a food preservative.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid-d4 | 1190021-70-5 | 98.7% | 2.5 MG
Adefovir-d4 is the deuterium labeled Adefovir, an adenosine monophosphate analog antiviral agent. After intracellular conversion to Adefovir diphosphate, it inhibits HBV DNA polymerase, with an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. It exhibits good antiviral activity against several viruses, including HBV and herpesviruses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes into drug molecules can affect pharmacokinetic and metabolic profiles.
Medchemexpress LLC Pyrrolidin-3-ol-d5 | 1219805-52-3 | 92.15 g/mol | C4H4D5NO | 10 MG
Pyrrolidin-3-ol-d5 is the deuterium-labeled analogue of pyrrolidin-3-ol used as a stable isotope tracer and internal standard in analytical and research applications.
- Deuterated tracer for mass spectrometry and isotope dilution assays.
- Isotopic enrichment: 97 atom % D.
- Molecular formula C4H4D5NO.
- Molecular weight 92.15 g/mol.
- Available in small quantities suitable for analytical standards, e.g., 10 mg packaging.
Medchemexpress LLC Carbamazepine-d8 | 1538624-35-9 | 1 MG
Carbamazepine-d8 is the deuterium labeled Carbamazepine. It is a sodium channel blocker and an anticonvulsant agent, with an IC50 of 131 μM. This compound is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Vericiguat-d3 hydrochloride | 1350653-20-1 | 99.8% | 465.86 | C19H14D3ClF2N8O2 | 10 MG
Vericiguat-d3 hydrochloride is the deuterated hydrochloride salt of vericiguat supplied for analytical and research use. It is designed to provide tracer functionality and to serve as an internal standard in quantitative assays such as NMR, GC-MS, and LC-MS.
- Provides deuterium-labeled tracer functionality for analytical studies.
- Intended as an internal standard for NMR, GC-MS, and LC-MS quantitation.
- High purity (≈99.8%) suitable for analytical applications.
- Solid powder form; protect from light and store under nitrogen.
- Recommended solvent storage: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC Thiamethoxam-d3 | 1294048-82-0 | 99.0% | 1 MG
Thiamethoxam-d3 is the deuterium labeled Thiamethoxam. Thiamethoxam is a broad spectrum neonicotinoid insecticide.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.